Jeffrey R. Gruen, MD Chairman - Advisory Board

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Professor of Pediatrics, Genetics, and Investigative Medicine; Yale Child Health Research Center; Yale University School of Medicine

Dr. Gruen has been at Yale since his internship in pediatrics in 1981. Dr. Gruen formally joined the faculty at Yale in 1988, splitting his time as a neonatology attending in the Newborn Intensive Care Unit (NICU) at Yale-New Haven Hospital and his lab. By 2000, the focus of his lab turned to mapping and identifying the reading disability (dyslexia) gene locus on chromosome 6 (DYX2). His lab was the first to generate high-resolution genetic markers, genetic association maps, and gene expression maps of DYX2. These studies led to the identification of DCDC2, a dyslexia gene that was cited by the journal Science as the 5th top breakthrough of 2005. The lab completed an NIH funded clinical study of DCDC2 and other genes related to reading and language in 14,000+ children and mothers, allowing for the identification of transcriptional control element called READ1, and READ1 alleles both detrimental and protective for reading disability and language impairment.  In addition to his research, Dr. Gruen continues practice neonatology at the Children’s Hospital at Yale-New Haven. He received his BS and his MD degrees from Tulane University in New Orleans.

Dr. Jan Frijters, PhD Member - Advisory Board

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Associate Professor, Brock University

Jan Frijters, PhD is a Developmental Psychologist who specializes in reading disability, motivation, and statistical methods for evaluating intervention outcomes. With over 20 years of experience in implementing and evaluating reading interventions for the most severely disabled readers, his primary concern is understanding the reasons why children respond differentially to those interventions. His statistical expertise focuses on techniques such as multilevel modeling, person-centered, and structural equation modeling approaches that can help sort out how developmental processes unfold over time and within specific learning contexts. Several large collaborative projects are underway with collaborators in Beijing and Xi’an China, the University of Stavanger in Norway, Yale University and Georgia State University in the US. These ongoing studies focus on the most severely challenged children, adolescents and adults: providing and evaluating intervention, examining the genetic and brain basis for reading difficulties, and examining how neuropsychological characteristics interact with these factors.

Today, Jan’s work is funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the Institute of Education Sciences, and the Manton Foundation. He was recently was awarded the Albert J. Harris Research Award from the International Reading Association.

David Gruber MD, MBA Member - Advisory Board

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David Gruber MD, MBA is a Managing Director and Director of Research with the Alvarez and Marsal Healthcare Industry Group (HIG) in New York, specializing in analytics, strategy, new ventures/business development, due diligence and health benefits. Before joining A&M, he spent three years as the Founder of Healthcare Convergence Associates, a consulting firm focused on the convergence of healthcare, technology and the consumer where he was also involved in three healthcare-related IT start-ups.

Until 2008, Dr. Gruber was Vice President of Corporate Development and New Ventures with the Johnson & Johnson Consumer Group of Companies. His primary focus was in dermatology / aesthetics, consumer engagement and wireless health across the company. In 1995-2004, he worked on Wall Street as a top-ten rated medical supplies and devices analyst at Lehman Brothers, Piper Jaffray and Sanford Bernstein.

Prior to entering Wall Street, Dr. Gruber was Vice President of Planning and Business Development for the $1.6 billion healthcare group at Bristol-Myers that included Zimmer, ConvaTec, Linvatec and Xomed-Treace.

Dr. Gruber is a magna cum laude graduate of a six-year BS-MD program, having received a bachelor’s degree from Sophie Davis School of Biomedical Education, CCNY in 1981 and a medical degree from the Mt. Sinai School of Medicine in 1983. He also has an MBA from Columbia University, and was a Kellogg Foundation National Fellow. Dr. Gruber is currently a Senior Fellow, Healthcare Innovation and Technology Lab (HITLAB) at Columbia Presbyterian. He is a re-elected Trustee on the Board of Education in Teaneck, NJ where he lives with his wife and three children.

Dr. Henry “Harv” Rinder Member - Advisory Board

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Henry M. Rinder, MD, FASCP; Professor of Laboratory Medicine & Internal Medicine (Hematology); Yale-New Haven Hospital New Haven, CT

Dr. Rinder attended Yale University for undergraduate studies and then the University of Vermont College of Medicine. Dr. Rinder teaches residents, fellows, postdoctoral and graduate students and at continuing education courses organized through the Yale Cancer Center, and the Departments of Internal Medicine and Laboratory Medicine. Dr. Rinder is actively involved in teaching at the graduate level through the Laboratory Medicine and Hematology teaching programs at the Yale School of Medicine.

After training in internal medicine and hematology, he went on to post-doctoral work in clinical pathology. His laboratory research focuses on cell-based diagnostics relevant to the basic biology of hemostasis and inflammation. He has evaluated the role of thrombin and complement in platelet dysfunction following extracorporeal circulation, studies of metabolic changes during platelet storage, hypercoagulability in drug abuse, and platelet function under the control of growth factors.

Dr. Rinder serves on the Board of Directors of the American Society for Clinical Pathology (ASCP) and works as the chair of the ASCP Commission on Continuing Professional Development.

Dr. Mark E. Mahone Member - Advisory Board

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Director of the Department of Neuropsychology at the Kennedy Krieger Institute, Professor of Psychiatry and Behavioral Sciences at the Johns Hopkins University School of Medicine

Dr. Mark Mahone is a licensed psychologist with board certification in Clinical Neuropsychology (with subspecialty certification in Pediatric Neuropsychology) from the American Board of Professional Psychology, a fellow of the National Academy of Neuropsychology and the American Psychological Association, and immediate Past-President of the American Academy of Clinical Neuropsychology (AACN). Dr. Mahone is presently Director of the Intellectual and Developmental Disabilities Research Center (IDDRC; U54 HD079123) at Kennedy Krieger Institute and on the core faculty for the Maternal and Child Health Bureau (MCHB) Leadership Education Excellence in Caring for Children with Neurodevelopmental and Related Disabilities (LEND) Program (6T73MC0019). Dr. Mahone is an editorial board member for five journals, including: Child Neuropsychology, Assessment, Developmental Neuropsychology, Archives of Clinical Neuropsychology, and The Clinical Neuropsychologist, and is Associate Editor for The Journal of the International Neuropsychological Society. 

Maureen W. Lovett, Ph.D., Child Psychology Member - Advisory Board

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Senior Scientist In The Neurosciences And Mental Health Program At The Hospital For Sick Children, Professor Of Paediatrics At The University Of Toronto

Maureen W. Lovett is Founder and Director of the Hospital’s Learning Disabilities Research Program, a clinical research group that develops and evaluates intervention programs for children and youth who struggle to learn to read. She has contributed to learning disabilities research and practice for the past 35 years, and is known internationally for her research on intervention. She, her team, and her colleagues have created interventions for children and teens with severe reading disabilities, evaluated their efficacy in controlled designs, and scaled interventions up in school systems. This research has been funded by operating grants from NICHD (NIH) and the Institute for Education Sciences (IES, the US Department of Education), as well as by provincial and federal agencies in Canada. Dr. Lovett is the 2017 recipient of the Samuel T Orton award, the highest honor of the International Dyslexia Association recognizing those who make a vital contribution to the scientific understanding of dyslexia.

Dr. Lovett’s research includes a substantial knowledge translation effort. The research interventions developed by her group at SickKids are now available to help struggling readers in elementary, middle, and high schools in school boards across Canada. First published by The Hospital for Sick Children as EmpowerTM Reading in 2006, the group has trained and mentored >2200 teachers who have taught >31,000 children and youth in the first decade of translation efforts.